Head, Portfolio Management Job at Sanofi, Cambridge, MA

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  • Sanofi
  • Cambridge, MA

Job Description

Job Description

Job Title: Head, Market Access Portfolio Strategy

Location: Cambridge, MA , Morristown, NJ

About the job

We are an innovative global healthcare company, committed to transforming the lives of people with immune challenges, rare diseases and blood disorders, cancers, and neurological disorders. From R&D to sales, our talented teams work together, revolutionizing treatment, continually improving products, understanding unmet needs, and connecting communities. We chase the miracles of science every single day, pursuing Progress to make a real impact on millions of patients around the world.​

Position Summary:

The Head, Market Access Portfolio Strategy is a strategic connector responsible for integrating payer strategies, scaling long-term Value & Access (V&A) capabilities, embedding AI-powered solutions, and leading early-stage access planning across a complex and diverse portfolio. This role directly supports the market access strategy for high-impact customer groups—including the Big 3 (Zinc/CVS, Ascent/ESI, Emisar/United/OptumRx)—by supporting the three dedicated Account Heads with coordinated content, pricing frameworks, and pull-through strategies that span therapeutic areas.

The role also maintains a broad enterprise view of market access profitability, including GTN dynamics, access investment trade-offs, and payer segmentation strategy—ensuring the organization maximizes value realization while enhancing executional efficiency across brands and development stages.

Main Responsibilities:

  • Serve as the enterprise connector across Value & Access, unifying execution across therapeutic areas and enabling coordinated customer, pricing, and pull-through strategies.

  • Lead a senior team across HEVA, customer marketing, future V&A enablement, and portfolio execution to drive enterprise value.

  • Support BD assets from US perspective, shaping Target Product Profiles, GTN assumptions, and payer value hypotheses.

  • Guide payer evidence planning and ensure seamless handoff to brand V&A teams in coordination with global access functions.

  • Build scalable, AI-enabled tools and workflows to accelerate delivery of payer materials, reduce vendor costs, and modernize V&A content operations.

  • Lead alignment of payer strategy for the Big 3 (Zinc/CVS, Ascent/ESI, Emisar/United/OptumRx), partnering with Account Heads to drive impact through integrated pricing, contracting, and customer engagement models.

  • Responsible for GOA 1 contract approvals across specialty portfolio

  • Lead 20% of market access brand budget for dynamic resource allocation across market access

  • Partner with HEVA and insights to embed GTN trends and macroeconomic factors into access strategy.

  • Oversee operational execution, resource prioritization, and KPI tracking across market access initiatives.

  • Develop future V&A talent through capability planning, mentorship, and training to build a high-performing, future-ready team.

About You

Required Qualifications:

  • 10+ years of progressive experience in market access, payer strategy, pricing, or related functions within pharmaceutical or biotech industries.

  • Deep expertise in GTN drivers, payer landscape, and specialty product market access across diverse therapeutic areas.

  • Proven experience managing cross-functional teams and driving enterprise-level strategic projects.

  • Demonstrated success implementing digital or AI-enabled capabilities in commercial environments.

  • Ability to operate effectively at both strategic and tactical levels within matrixed organizations.

Preferred Qualifications:

  • Experience integrating AI or advanced analytics platforms into payer strategy or pricing operations.

  • Exceptional change management skills to lead capability evolution in dynamic market environments.

  • Track record of driving cross-business synergies and translating strategic insights into actionable plans.

Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.​​

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.​

  • ​Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.​

  • ​Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.​

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.​

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Job Tags

Contract work,

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